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What is TB-500? Understanding This Research Compound
Peptide Guides

What is TB-500? Understanding This Research Compound

3 FEB 20255 min read32,983 views

TB-500 (Thymosin Beta-4) is a 43-amino-acid research peptide with a molecular weight of 889 g/mol. This guide covers its structure, supply form, and laboratory handling.

TB-500: Quick facts

Full nameThymosin Beta-4 (synthetic analogue)
Amino acids43
Molecular formulaC₃₈H₆₈N₁₀O₁₄
Molecular weight889.01 g/mol
Supply formLyophilised powder
Intended useScientific research only

What is TB-500?

TB-500 is a synthetic version of Thymosin Beta-4, a naturally occurring peptide found in most human and animal tissues. It is a 43-amino-acid sequence that has been the subject of considerable scientific study due to its structural role in actin-binding and its presence in a wide variety of biological systems.

At My UK Peptides, TB-500 is supplied as a lyophilised powder for research use only. It is not intended for human or veterinary use, and should be handled exclusively in a properly equipped laboratory setting.

Molecular structure and properties

TB-500 belongs to a family of actin-sequestering proteins. Its molecular structure features a central LKKTET motif — a short sequence that is thought to play a central role in actin binding. The peptide is hydrophilic and soluble in aqueous solutions, making reconstitution in bacteriostatic water straightforward for most research applications.

Supply form and storage

TB-500 arrives lyophilised in sealed glass vials. This freeze-dried form is stable at room temperature for short periods during transit, but should be stored at −20°C on receipt for any storage longer than one week. Once reconstituted, keep the solution refrigerated at 2–8°C and use within 28 days. Do not freeze reconstituted solutions.

Reconstitution

Reconstitute using bacteriostatic water. For a 5 mg vial, adding 2 ml of bacteriostatic water gives a concentration of 2.5 mg/ml (2,500 mcg/ml). Each 0.1 ml drawn equates to 250 mcg. Always add the solvent slowly to the vial wall to prevent denaturation.

Important: TB-500 from My UK Peptides is a research compound only. It is not for human or animal use. For research use only in accordance with applicable regulations.

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